Drug intelligence / Profile preview

Compound Huangqi

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

Compound Huangqi is a traditional Chinese medicine (TCM) formulation whose principal ingredient is *Astragalus* root (commonly known as "Huang Qi"), often combined with other herbs. The main active components of Astragalus include polysaccharides, saponins (notably astragaloside IV), flavonoids, and isoflavones such as calycosin and formononetin. These compounds are believed to contribute to its immunomodulatory, anti-inflammatory, antioxidant, anti-diabetic, and cardiovascular protective effects[1][5][6]. In TCM practice and modern research contexts, Compound Huangqi formulations are used for immune support; to treat fatigue; for adjunctive therapy in heart disease and diabetes; for kidney protection; and sometimes in combination therapies against viral infections[2][3][5]. Mechanistically, the bioactive constituents modulate immune responses by stimulating or regulating cytokine production and enhancing resistance to stressors. The precise mechanism depends on the specific herbal composition of the formulation.

Brand names
Compound Huangqi
Other names
huang qi compoundhuangqi fufangastragalus compound黄芪复方
02

Targets

ESR2 (ERβ)AR (Adrenergic receptors)EGFR T790M (Epidermal growth factor receptor T790M mutant)CASP3 (Caspase-3)IL-6 (Interleukin 6)

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