Drug intelligence / Profile preview

Compound Hypotensive Tablets

Development stage
Phase 4
Modality
Small Molecules
Administration
Oral
01

Overview

Compound Hypotensive Tablets, also known as Beijing Hypotensive No. 0, is a fixed-dose combination pharmaceutical drug used for the treatment of mild to moderate essential hypertension. It combines five active ingredients: reserpine, hydrochlorothiazide, triamterene, dihydralazine sulfate, and chlordiazepoxide. This multi-component approach targets various physiological pathways involved in blood pressure regulation, offering a synergistic hypotensive effect. The drug is recognized for its efficacy, affordability, and long-standing use in China for hypertension management.

Brand names
Beijing Hypotensive No. 0降压0号
Other names
复方利血平氨苯蝶啶片No. 0
02

Targets

VMAT1 (Vesicular monoamine transporter type 1)SLC12A3 (Thiazide-sensitive sodium-chloride cotransporter)VMAT2 (Vesicular monoamine transporter 2)ENaC

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