compound kushen injection + levofloxacin

Compound Kushen Injection + levofloxacin is a combination therapy consisting of **Compound Kushen Injection (CKI)**, a traditional Chinese medicine injection derived from the roots of Sophora flavescens and Smilax glabra, and **levofloxacin**, a synthetic third-generation fluoroquinolone antibiotic. CKI is reported to have immunomodulatory, anti-inflammatory, and antitumor activities, often explored as an adjunct to chemotherapy to enhance clinical responses and immune function. Levofloxacin acts primarily by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication, thereby exerting bactericidal activity against a range of gram-positive and gram-negative bacteria. The combination may be used in specific settings such as infection prophylaxis or treatment during cancer therapies to leverage both antimicrobial and potential complementary immunomodulatory effects[1][5].