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compound kushen salicylic acid powder
- Development stage
- Unknown
- Lead developer
- Shanghai Xiao Fang Pharmaceutical
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Compound Kushen Salicylic Acid Powder (复方苦参水杨酸散) is an over-the-counter (OTC) topical herbal-chemical combination drug developed and marketed by Shanghai Xiao Fang Pharmaceutical under the brand name Xinlong. It is formulated as a soak powder containing salicylic acid, benzoic acid, boric acid, and Kushen (Sophora flavescens root) extract. The combination acts synergistically to provide antifungal, keratolytic, antiseptic, and antipruritic effects. It is primarily indicated for the treatment of tinea manus and tinea pedis (fungal infections of the hands and feet, commonly known as athlete's foot). The powder is dissolved in warm water to create a foot or hand soak.
- Brand names
- XinlongXinlong Zuguan信龙信龙足光信龙足光散
- Other names
- Compound Kushen Salicylic Acid PowderZuguan Powder复方苦参水杨酸散足光粉足光散
02
Targets
AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)CASP3 (Caspase-3)CHEK1 (Checkpoint kinase 1)ERBB2 (Erb-b2 receptor tyrosine kinase 2)IL-6 (Interleukin 6)MMP2 (Matrix metalloproteinase-2)RELA (Nuclear Factor Kappa B Subunit p65)PIK3CA (Phosphoinositide 3-kinase alpha)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)STAT3 (Signal Transducer and Activator of Transcription 3)TP53 (Cellular Tumor Antigen p53 R175H)
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