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Compound lactobacillus acidophilus is a multi-strain probiotic preparation typically containing *Lactobacillus acidophilus*, *Lactobacillus bulgaricus*, and *Streptococcus thermophilus*. It is primarily utilized in clinical practice to restore and maintain the balance of gastrointestinal microbiota. In the context of *Helicobacter pylori* infection, it is frequently employed as an adjunctive therapy alongside standard quadruple regimens (comprising a proton pump inhibitor, bismuth, and two antibiotics). The introduction of these beneficial bacteria helps to competitively inhibit *H. pylori* colonization, modulate the gastric immune response, and mitigate the gastrointestinal side effects commonly associated with intensive antibiotic treatment, thereby potentially improving overall eradication rates in patients with chronic gastritis or peptic ulcers.
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