Drug intelligence / Profile preview

compound lactobacillus acidophilus (Chongqing University Cancer Hospital)

Development stage
Unknown
Lead developer
Chongqing University Cancer Hospital
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Compound lactobacillus acidophilus is a multi-strain probiotic preparation typically containing *Lactobacillus acidophilus*, *Lactobacillus bulgaricus*, and *Streptococcus thermophilus*. It is primarily utilized in clinical practice to restore and maintain the balance of gastrointestinal microbiota. In the context of *Helicobacter pylori* infection, it is frequently employed as an adjunctive therapy alongside standard quadruple regimens (comprising a proton pump inhibitor, bismuth, and two antibiotics). The introduction of these beneficial bacteria helps to competitively inhibit *H. pylori* colonization, modulate the gastric immune response, and mitigate the gastrointestinal side effects commonly associated with intensive antibiotic treatment, thereby potentially improving overall eradication rates in patients with chronic gastritis or peptic ulcers.

Brand names
MeichangMeichang'an
Other names
Compound Lactobacillus Acidophilus TabletsFufang Shisuan Rushangan Pian
02

Targets

PRR (Pattern recognition receptors)

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