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Compound Mylabris capsules (also known as Fufang Banmao Jiaonang) is a traditional Chinese patent medicine widely used in China as an adjuvant therapy for various malignant tumors, including hepatocellular carcinoma, lung cancer, rectal cancer, and malignant lymphoma. The formulation consists of 11 traditional Chinese medicinal ingredients, with Mylabris (blister beetle) as the primary active component, alongside ginseng, astragalus root, Siberian ginseng, sparganium, barbed skullcap, zedoary, cornus fruit, glossy privet fruit, bear bile powder, and licorice root. The primary active compound of Mylabris is cantharidin, which acts as an inhibitor of protein phosphatase 2A (PP2A) and protein phosphatase 1 (PP1), leading to G2/M phase cell cycle arrest and apoptosis in cancer cells. Compound Mylabris capsules are typically administered orally and are often evaluated in combination with other therapies, such as transarterial chemoembolization (TACE) and chemotherapy, to improve survival outcomes and quality of life in cancer patients.
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