Drug intelligence / Profile preview

Compound Nanxing Pain Paste

Development stage
Phase 4
Lead developer
Lianyungang Kanion
Modality
Classical Binding Small Molecules → Small Molecules
Administration
Topical
01

Overview

Compound Nanxing Pain Paste is a traditional Chinese medicine (TCM) topical formulation used primarily for the relief of pain and inflammation associated with musculoskeletal conditions such as chronic knee synovitis and rheumatic arthritis. The paste is applied externally to affected areas. Its formula typically includes herbal ingredients such as Rhizoma Arisaematis (Nan Xing), Radix Aconiti, camphor, myrrh, and other plant-based substances. The main active components are believed to be alkaloids from these herbs, which exert analgesic (pain-relieving) effects. Clinical studies have shown that the paste can reduce pain, swelling, and improve joint function in patients with chronic knee synovitis[1][3][4][7]. The mechanism of action is based on TCM principles—promoting blood circulation, dispelling wind-dampness, reducing swelling—and may involve local anti-inflammatory and analgesic effects.

Brand names
Compound Nanxing Pain Paste
Other names
Nanxing Compound Pain Paste复方南星止痛膏
02

Targets

IL8 (C-X-C Motif Chemokine Ligand 8)IL1A (Interleukin 1 alpha)IL-6 (Interleukin 6)VEGFA (Vascular endothelial growth factor A)COXNaV (Voltage-gated sodium channels)

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