Drug intelligence / Profile preview

compound paracetamol and amantadine hydrochloride

Development stage
Unknown
Lead developer
Shandong Chenxin Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Huakebi is a brand name for a compound paracetamol and amantadine hydrochloride capsule, a common over-the-counter (OTC) medication in China used to treat symptoms of the common cold and influenza. Developed and manufactured by Shandong Chenxin Pharmaceutical (SCCPC), the combination typically includes paracetamol for pain and fever relief, amantadine hydrochloride as an antiviral agent against influenza A, chlorpheniramine maleate to reduce allergic symptoms like runny nose and sneezing, caffeine to counteract the sedative effects of the antihistamine, and artificial bezoar for its traditional antipyretic and sedative properties.

Brand names
Huakebi华克比
Other names
Compound Paracetamol and Amantadine Hydrochloride Capsules复方氨酚烷胺胶囊
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)CHRM2 (M2)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)NMDAR (Glutamate receptor ionotropic, NMDA)

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