Drug intelligence / Profile preview

Compound Platycladus Orientalis Tincture

Development stage
Unknown
Lead developer
Shanghai Skin Disease Hospital
Administration
Topical
01

Overview

Compound Platycladus Orientalis Tincture (CPT) is an ethanol-based polyherbal tincture developed as an in-hospital topical preparation by Shanghai Dermatology Hospital (Shanghai Skin Disease Hospital) for the treatment of alopecia, including androgenetic alopecia (AGA) and alopecia areata. The formulation consists of Platycladi Cacumen (Chinese arborvitae twig and leaf), Szechwan Chinaberry Fruit (川楝子, Toosendan Fructus), and Herba Speranskiae Tuberculatae (透骨草, Tuberculate Speranskia Herb). CPT promotes hair regrowth and hair-cycle progression by activating the Wnt/β-catenin signaling pathway, enhancing dermal papilla cell viability, and modulating androgen-related and apoptosis/proliferation pathways.

Other names
Fufang Cebai DingFufang Cebaiye Ding复方侧柏叶酊复方侧柏酊
02

Targets

AR (Adrenergic receptors)CTNNB1 (Beta-catenin)VEGFA (Vascular endothelial growth factor A)

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