Drug intelligence / Profile preview

compound pseudolaric tincture

Development stage
Unknown
Lead developer
Henan Purui Pharmaceutical
Modality
Small Molecules
Administration
Topical
01

Overview

Compound Pseudolaric Tincture is a topical antifungal medication widely used in Traditional Chinese Medicine and modern dermatology in China. Developed and manufactured by Henan Purui Pharmaceutical, this formulation typically consists of extracts from *Cortex Pseudolaricis* (the root bark of *Pseudolaris kaempferi*), combined with benzoic acid and salicylic acid. The primary active constituent, pseudolaric acid B, exerts potent antifungal effects by binding to the colchicine site of tubulin, thereby inhibiting microtubule polymerization and disrupting fungal cell division. Salicylic acid serves as a keratolytic agent, softening the stratum corneum to enhance the penetration of the antifungal components, while benzoic acid provides additional antiseptic and antifungal properties. It is indicated for the treatment of various superficial fungal skin infections, including tinea pedis (athlete's foot), tinea corporis (ringworm), and tinea cruris (jock itch).

Brand names
复方土槿皮酊
Other names
Compound Cortex Pseudolaricis TinctureFufang Tujinpi Ding
02

Targets

TUBB (Tubulin (alpha and beta subunits))

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