Compound Qingdai Capsules

Compound Qingdai Capsules (Fufang Qingdai Jiaonang) is a Traditional Chinese Medicine (TCM) formulation widely utilized in China for the treatment of moderate-to-severe plaque psoriasis. The primary active component is Qingdai (Indigo Naturalis), which contains the bis-indole alkaloids indigo and indirubin. These compounds exert therapeutic effects by acting as agonists for the aryl hydrocarbon receptor (AhR) and inhibitors of cyclin-dependent kinases (CDKs), which collectively work to normalize keratinocyte differentiation, inhibit excessive skin cell proliferation, and modulate the production of pro-inflammatory cytokines such as IL-17 and TNF-alpha. The formulation typically includes auxiliary herbs such as Salvia miltiorrhiza and Smilax glabra to improve microcirculation and clear heat-toxins. Clinical studies, including randomized controlled trials, have evaluated its efficacy in improving Psoriasis Area and Severity Index (PASI) scores and patient quality of life.

Brand names

Fufang Qingdai Jiaonang

Other names

Indigo Naturalis Compound CapsulesCompound Qingdai Capsules