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Compound Qingre
- Development stage
- Unknown
- Lead developer
- Beijing Friendship Hospital
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Compound Qingre Granule is a Chinese patent medicine (herbal formulation) developed by researchers at Beijing Friendship Hospital, specifically Dr. Shuwen Zhang and Dr. Baoen Wang. It is primarily used to treat Fever of Unknown Origin (FUO) characterized by Excess-heat Syndrome in Traditional Chinese Medicine (TCM). The drug is designed to modulate the inflammatory response by influencing levels of pro-inflammatory cytokines and markers such as tumor necrosis factor (TNF), interleukin-1 (IL-1), interleukin-6 (IL-6), and triggering receptor expressed on myeloid cells-1 (TREM-1). It is typically administered orally in a granule dosage form.
- Brand names
- Compound Qingre Granule
- Other names
- Fufang Qingre Keli
02
Targets
TREM1 (Triggering receptor expressed on myeloid cells 1)IL-6 (Interleukin 6)IL1A (Interleukin 1 alpha)
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