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Compound Shenxiong Dripping Pills

Development stage: Unknown
Lead developer: Eight Plus One Pharmaceutical
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Oral

Overview

Compound Shenxiong Dripping Pills is a traditional Chinese medicine (TCM) formulation developed by Guilin Eight Plus One Pharmaceutical Research Co., Ltd. for the treatment of coronary heart disease and angina pectoris, specifically targeting the 'Qi deficiency and blood stasis' syndrome. The formulation is composed of extracts from *Salvia miltiorrhiza* (Danshen), *Ligusticum chuanxiong* (Chuanxiong), and *Panax notoginseng* (Sanqi). Its therapeutic mechanism involves promoting blood circulation, resolving blood stasis, and improving myocardial microcirculation and oxygen supply. It is administered as dripping pills, a dosage form designed for rapid absorption. Clinical development has reached Phase 2 in China, focusing on dose-finding and preliminary efficacy in patients with stable angina pectoris.

Brand names: Compound Shenxiong Dripping Pills
Other names: Fufang Shenxiong Diwan

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