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Compound Zhuye Shigao is a Traditional Chinese Medicine (TCM) formulation, typically prepared as a granule, based on the classic Zhuye Shigao Tang. Its primary active components include *Lophatherum gracile* (bamboo leaf) and *Gypsum fibrosum* (gypsum). The preparation is used in clinical practice to treat inflammatory conditions of the upper respiratory and oral mucosa, specifically recurrent oral ulcers and chronic pharyngitis. It functions by clearing internal heat and promoting fluid production. Clinical research, including studies conducted by the PLA General Hospital, evaluates its efficacy in reducing pain and promoting mucosal healing.
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