Drug intelligence / Profile preview

condarive sodium

Development stage
Unknown
Lead developer
Guangdong Dongyangguang Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Condarive sodium (HEC110114) is a small molecule direct-acting antiviral (DAA) developed by Guangdong Dongyangguang Pharmaceutical (HEC Pharm) for the treatment of chronic hepatitis C virus (HCV) infection. It functions as an inhibitor of the HCV NS3/4A protease, an enzyme essential for the processing of the viral polyprotein into functional units required for viral replication. In clinical studies, such as the Phase 1 trial CTR20171515, condarive sodium has been evaluated for its safety, tolerability, and pharmacokinetic properties in healthy subjects, including assessments of single and multiple ascending doses and food effects. It is typically investigated as a component of combination regimens aimed at achieving high sustained virologic response (SVR) rates across multiple HCV genotypes.

Other names
康达瑞韦钠
02

Targets

NS3/4A (Hepatitis C virus nonstructural protein 3/4A serine protease)

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