Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Conditioning-Nanfang Hospital, Southern Medical University-acute myeloid leukemia
- Development stage
- Unknown
- Lead developer
- Nanfang Hospital, Southern Medical University
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
This entry refers to the specific conditioning chemotherapy regimens utilized by Nanfang Hospital, Southern Medical University, in their hematopoietic stem cell microtransplantation (MST) protocol for patients with acute myeloid leukemia (AML). The protocol employs different regimens based on the patient's clinical status: patients in complete remission (CR) receive high-dose cytarabine (HD Ara-C), while those not in CR receive either the IAC regimen (a combination of idarubicin, cytarabine, and cladribine) or HD Ara-C. These regimens are designed to debulk leukemia cells and provide sufficient immunosuppression to allow for the infusion of HLA-mismatched donor stem cells without the need for full myeloablation or graft-versus-host disease (GVHD) prophylaxis, which is a hallmark of the microtransplantation approach.
- Other names
- IAC regimenHD Ara-C conditioningNanfang Hospital AML MST conditioning regimen
02
Targets
DNA polymerase familyDNATOP2A (DNA topoisomerase II)RNR (Ribonucleotide reductase)
Beyond the preview
Go deeper on Conditioning-Nanfang Hospital, Southern Medical University-acute myeloid leukemia.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Conditioning-Nanfang Hospital, Southern Medical University-acute myeloid leukemia.