Drug intelligence / Profile preview

CONJUMAB-A

Development stage
Unknown
Lead developer
Intellect Neurosciences
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravitreal
01

Overview

CONJUMAB-A is an antibody-drug conjugate (ADC) developed by Intellect Neurosciences for the treatment of Age-related Macular Degeneration (AMD). It is the lead candidate from the company's CONJUMAB platform, which utilizes a site-specific conjugation technology to attach antioxidant and anti-inflammatory small molecules to monoclonal antibodies. In the case of CONJUMAB-A, the antibody component is designed to target amyloid-beta (Aβ) deposits, which are associated with the progression of geographic atrophy in AMD. By delivering a potent antioxidant payload directly to the site of pathology, the drug aims to reduce oxidative stress and inflammation while minimizing systemic exposure.

02

Targets

Aβ N-terminus (Amyloid beta peptide N-terminal epitope)

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