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Control toothpaste

Development stage: Unknown
Lead developer: Colgate-Palmolive
Modality: Small Molecules
Administration: Topical

Overview

A non-fluoridated placebo toothpaste formulation developed by Colgate-Palmolive for use as a negative control in clinical trials. It contains the base ingredients of a standard toothpaste but lacks active anti-cavity agents such as fluoride or arginine. It is utilized in studies, such as those for dental caries, to provide a baseline for evaluating the remineralization and demineralization potential of experimental oral care products. In clinical trial contexts, it allows researchers to distinguish the therapeutic effects of active ingredients from the mechanical effects of brushing and the properties of the toothpaste vehicle.

Other names: Non-fluoride control toothpasteControl toothpaste containing no anti-cavity ingredients

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