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convalescent plasma-Aga Khan University-COVID-19

Development stage
Unknown
Lead developer
Aga Khan University
Administration
Intravenous
01

Overview

Convalescent plasma-Aga Khan University-COVID-19 is a passive immunotherapy developed and studied by Aga Khan University for the treatment of severe or critical COVID-19. The therapy involves the intravenous transfusion of plasma collected from donors who have recovered from SARS-CoV-2 infection. This plasma contains high titers of neutralizing antibodies and other proteins that target the SARS-CoV-2 virus, aiming to neutralize viral particles, suppress viremia, and limit the progression of the infection. It was primarily investigated in a non-randomized, open-label clinical trial at Aga Khan University Hospital in Karachi, Pakistan, to evaluate its safety and efficacy in reducing mortality and the length of hospital stay in hospitalized patients.

Other names
Convalescent Plasma (CP)COVID-19 convalescent plasmaCOVID19 convalescent plasmaCOVID 19 convalescent plasma
02

Targets

S2 (SARS-CoV-2 spike S2 subunit)S1 (SARS-CoV-2 spike S1 subunit)

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