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convalescent plasma-Azienda Socio Sanitaria Territoriale di Mantova-COVID-19

Development stage: Unknown
Lead developer: Azienda Socio Sanitaria Territoriale di Mantova
Administration: Intravenous

Overview

Convalescent plasma-Azienda Socio Sanitaria Territoriale di Mantova-COVID-19 is an investigational biological therapy developed by the Azienda Socio Sanitaria Territoriale (ASST) di Mantova in Italy. It consists of plasma collected from donors who have recovered from COVID-19, containing high titers of neutralizing antibodies against the SARS-CoV-2 virus. The therapy aims to provide passive immunity to infected individuals, particularly elderly patients in nursing home settings, to reduce viral load and improve clinical outcomes. It was evaluated in a Phase 2 clinical trial (NCT04569188) focusing on safety and efficacy in the elderly population during the pandemic.

Other names: convalescent plasmahyperimmune plasma

Targets

RBD (SARS-CoV-2 spike receptor-binding domain)

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