convalescent plasma-Hospital San Vicente Fundación-COVID-19

Convalescent plasma-Hospital San Vicente Fundación-COVID-19 refers to the use of COVID-19 convalescent plasma (CCP) as an investigational treatment in a clinical trial setting led by the Hospital San Vicente Fundación. Convalescent plasma is a form of passive immunotherapy where plasma containing high titers of neutralizing antibodies is collected from donors who have recovered from SARS-CoV-2 infection and transfused into patients with active, severe COVID-19. The primary mechanism of action involves the binding of these donor-derived antibodies to the SARS-CoV-2 spike protein, thereby neutralizing the virus, preventing its entry into host cells, and potentially modulating the host's inflammatory response. This specific intervention was evaluated in a Phase 3 randomized, open-label trial to determine its efficacy in reducing mortality among critically ill patients in the intensive care unit.

Other names

convalescent plasmaCOVID-19 convalescent plasmaCOVID19 convalescent plasmaCOVID 19 convalescent plasma