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Convalescent Plasma-Maranatha Christian University-COVID-19

Development stage: Unknown
Lead developer: Maranatha Christian University
Modality: Antibody-Based Therapeutics
Administration: Intravenous

Overview

Convalescent Plasma-Maranatha Christian University-COVID-19 refers to a specific convalescent plasma therapy evaluated by researchers at Maranatha Christian University in Indonesia. This biologic therapy utilizes plasma collected from individuals who have recovered from COVID-19, which contains high titers of polyclonal neutralizing antibodies (specifically 1:320 in the studied cohort) against the SARS-CoV-2 virus. The treatment is administered intravenously to provide passive immunization, aiming to neutralize the virus and prevent the progression of severe disease in hospitalized, non-intubated patients. It has been utilized under emergency approval in Indonesia as part of a broader multicenter clinical evaluation.

Other names: Convalescent Plasma TherapyCPT

Targets

RBD (SARS-CoV-2 spike receptor-binding domain)S2 (SARS-CoV-2 spike S2 subunit)S1-NTD (SARS-CoV-2 spike S1 N-terminal domain)

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