conventional liberal fluid regimen-Mahidol University

The conventional liberal fluid regimen-Mahidol University is a specific intraoperative fluid management protocol utilized as a control arm in clinical research conducted by Mahidol University, particularly for pediatric patients weighing less than 15 kg undergoing major abdominal surgery. This regimen involves the intravenous administration of crystalloid solutions calculated to cover maintenance fluid requirements (using the 4-2-1 rule), fasting fluid deficits, dehydration, and third-space losses. The liberal nature of the protocol refers to the comprehensive replacement of all estimated fluid losses, which is often contrasted with restricted or goal-directed fluid therapies that aim to minimize fluid overload. The primary objective of using this regimen in trials is to provide a standard-of-care baseline for comparing postoperative outcomes such as weight gain, gut function recovery, and pulmonary complications.

Other names

liberal fluid regimenconventional liberal fluid therapy