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Conventional symptomatic treatment-Alexandria University

Development stage
Unknown
Lead developer
University of Alexandria
Modality
Small Molecules
Administration
Topical
01

Overview

Conventional symptomatic treatment-Alexandria University refers to a specific multi-drug topical regimen used as a standard-of-care control arm in clinical trials conducted by Alexandria University for managing chemotherapy-induced oral mucositis (OM). The regimen consists of three distinct pharmaceutical products: **Oracure** (a gel typically containing choline salicylate and lidocaine), **BBC spray** (an anesthetic and antiseptic spray containing benzocaine, benzalkonium chloride, and cetylpyridinium chloride), and **Miconaz** (an antifungal oral gel containing miconazole). This combination is designed to provide comprehensive symptomatic relief by reducing pain and inflammation, providing local anesthesia, and preventing or treating secondary fungal infections such as oral candidiasis, which are common complications in pediatric leukemia patients undergoing chemotherapy.

Brand names
OracureBBC sprayMiconaz
Other names
Oracure + BBC spray + Miconaz
02

Targets

CYP51A1 (Sterol 14α-demethylase)

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