Drug intelligence / Profile preview

Coolprep Gold Powder

Development stage
Unknown
Lead developer
Taejoon Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Coolprep Gold Powder is an osmotic laxative formulation developed by Taejoon Pharmaceutical for gastrointestinal pretreatment. It is primarily indicated for bowel cleansing in preparation for colonoscopy, barium enema X-ray examinations, or abdominal surgery. The product is a low-volume (1-liter) polyethylene glycol (PEG) 3350-based powder that, when reconstituted, creates an iso-osmotic solution. It typically contains PEG 3350 along with electrolytes (sodium sulfate, sodium chloride, potassium chloride) and ascorbic acid/sodium ascorbate. The mechanism of action involves PEG 3350 acting as an osmotic agent that retains water within the intestinal lumen, thereby increasing stool volume and stimulating bowel movements to effectively clear the colon while the included electrolytes and ascorbic acid help maintain fluid balance and improve the cleansing effect.

Brand names
Coolprep Gold PowderCoolprep Gold
Other names
Polyethylene Glycol 3350PEG 3350PEG3350PEG-3350
02

Targets

Bulk water in the intestinal lumen and colonic contentsGas–liquid interface in intestinal contents

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