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Drug intelligence / Profile preview
copper (64Cu) chloride
- Development stage
- Unknown
- Lead developer
- ITEL
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Beta-minus Emitters → Radiopharmaceuticals, Positron Emitters → Radiopharmaceuticals, Small Molecules
- Administration
- Intravenous
01
Overview
Cupric chloride-64 (copper (64Cu) chloride) is a radiopharmaceutical diagnostic agent containing the positron-emitting isotope copper-64. Developed by ITEL Pharma, it is utilized as a tracer for Positron Emission Tomography (PET) imaging. The agent exploits the natural physiological role of copper and the upregulation of copper transporters, specifically the high-affinity copper uptake protein 1 (CTR1), in various pathological states. It is clinically applied in the detection and staging of several malignancies, including prostate cancer, glioblastoma, and breast cancer, as well as in the evaluation of copper metabolism in neurodegenerative diseases like Alzheimer's and cardiovascular conditions such as atherosclerosis.
- Other names
- cupric chloride-64copper-64 chloridecopper64 chloridecopper 64 chloride64Cu-copper chloride64Cu-CuCl2cupric chloride Cu 64
02
Targets
SLC31A1 (Human copper transporter 1)
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