Drug intelligence / Profile preview

copper (64Cu) chloride

Development stage
Unknown
Lead developer
ITEL
Modality
Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

Cupric chloride-64 (copper (64Cu) chloride) is a radiopharmaceutical diagnostic agent containing the positron-emitting isotope copper-64. Developed by ITEL Pharma, it is utilized as a tracer for Positron Emission Tomography (PET) imaging. The agent exploits the natural physiological role of copper and the upregulation of copper transporters, specifically the high-affinity copper uptake protein 1 (CTR1), in various pathological states. It is clinically applied in the detection and staging of several malignancies, including prostate cancer, glioblastoma, and breast cancer, as well as in the evaluation of copper metabolism in neurodegenerative diseases like Alzheimer's and cardiovascular conditions such as atherosclerosis.

Other names
cupric chloride-64copper-64 chloridecopper64 chloridecopper 64 chloride64Cu-copper chloride64Cu-CuCl2cupric chloride Cu 64
02

Targets

SLC31A1 (Human copper transporter 1)

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