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copper Cu 64 dotatate
- Development stage
- Approved
- Lead developer
- Radiomedix
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
Copper Cu 64 dotatate is a **radiopharmaceutical diagnostic agent** used with positron emission tomography (PET) to locate **somatostatin receptor-positive neuroendocrine tumors (NETs)** in adults. It consists of a somatostatin analog, dotatate, linked to the positron-emitting radioisotope copper-64. After intravenous administration, it binds to **somatostatin receptor type 2 (SSTR2)**, which is frequently overexpressed on NET cells, enabling tumor localization via PET imaging. The agent has a physical half-life of approximately 12.7 hours. The drug is marketed under the brand name Detectnet and was developed by RadioMedix, with commercial manufacturing by Curium[1][2][3][5][7][8][10].
- Brand names
- Detectnet
- Other names
- copper (64Cu) oxodotreotide
02
Targets
SSTR2 (Somatostatin receptor type 2)
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