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Coptidis Rhizoma Qu Taidu is a Traditional Chinese Medicine (TCM) botanical preparation derived from the rhizome of *Coptis chinensis* (Huang Lian). It is utilized as an external wash or bath for newborns with the therapeutic intent of "clearing fetal toxin" (Qu Taidu), a practice in TCM aimed at preventing neonatal skin ailments. The preparation is primarily being investigated by Xiyuan Hospital of the China Academy of Chinese Medical Sciences for its efficacy in preventing infant eczema. Its pharmacological activity is attributed to alkaloids such as berberine, which exhibit potent anti-inflammatory, antimicrobial, and antioxidant effects, potentially stabilizing the neonatal skin barrier and modulating local immune responses.
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