Drug intelligence / Profile preview

Coqun

Development stage
Unknown
Lead developer
Lupin
Modality
Small Molecules
Administration
Oral
01

Overview

Coqun is a specialized formulation of Coenzyme Q10 (CoQ10) combined with Vitamin E (specifically alpha-tocopheryl polyethylene glycol 1000 succinate, or TPGS), primarily used as a neuroprotective and antioxidant treatment in ophthalmology. It is available as a topical ophthalmic solution and an oral formulation. The topical version is often regulated as a Class IIb medical device in Europe and is designed to deliver CoQ10 to the retina to support mitochondrial function and reduce oxidative stress, which are critical factors in the progression of glaucoma. The oral version, Coqun OS, utilizes timed-release 'Miniactives' technology to ensure sustained plasma concentrations of CoQ10. Coqun is investigated for its ability to reduce retinal ganglion cell loss and improve visual cortical responses in patients with open-angle glaucoma, pseudo-exfoliative glaucoma, and retinopathy of prematurity.

Brand names
CoqunCoqun OS
Other names
Coqun dropCoQ10-MiniactivesCoQ-10-MiniactivesCoQ 10-MiniactivesCoqun OralCOQUN OS
02

Targets

OXPHOS (Mitochondrial OXPHOS complexes)ND1 (Mitochondrial electron transport chain complex I)

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