Drug intelligence / Profile preview

CoraVax

Development stage
Unknown
Lead developer
Bharat Biotech
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

CoraVax (BBV155) is a dual-antigen vaccine candidate developed by Thomas Jefferson University and Bharat Biotech. It utilizes a recombinant, inactivated rabies virus vector to express the SARS-CoV-2 spike protein. By leveraging the established safety and manufacturing infrastructure of the inactivated rabies vaccine platform, CoraVax is designed to provide protective immunity against both COVID-19 and rabies. The vaccine is particularly noted for its potential stability at standard refrigeration temperatures, facilitating distribution in regions with limited cold-chain infrastructure. Preclinical studies demonstrated robust neutralizing antibody responses against both pathogens, and the candidate has proceeded into Phase 1 clinical trials for safety and immunogenicity evaluation.

Brand names
CoraVax
Other names
inactivated SARS-CoV-2 vaccine + rabies vaccinerabies-vectored SARS-CoV-2 vaccineCORAVAXinactivated rabies-vectored COVID-19 vaccine
02

Targets

RABV-G (Rabies virus glycoprotein)SARS-CoV-2 spike

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