Drug intelligence / Profile preview

cordyceps cicadae ethanolic extract

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

Cordyceps cicadae ethanolic extract (CCM-EtOH) is an extract derived from the mycelia of *Cordyceps cicadae*, a well-known traditional Chinese herbal medicine. It is obtained through lyophilization and extraction with ethanol. Preclinical studies in a steroid-induced rat model of glaucoma have shown that CCM-EtOH can significantly lower intraocular pressure (IOP) and exhibits antioxidant activities. Its efficacy in IOP reduction was observed to be less than that of the aqueous extract (CCM-DW) in the same study. The antioxidant effects are evidenced by decreases in malondialdehyde and lactate dehydrogenase levels, and increases in catalase, superoxide dismutase, and glutathione peroxidase levels.

Other names
CCM-EtOH

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