Drug intelligence / Profile preview

cordyceps cicadae extract

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral, Topical, Ophthalmic
01

Overview

Cordyceps cicadae extract is a medicinal preparation derived from the fungus Cordyceps cicadae, traditionally used in Chinese medicine. It contains bioactive compounds including polysaccharides (62.7 mg/g), alditols (mainly mannitol, 110 mg/g), nucleosides (8.26 mg/g), protein (35.7 mg/g), and polyphenols (3.8 mg/g). A key active component is N6-(2-hydroxyethyl)-adenosine (HEA), present in higher concentrations in the water extract (3.9 mg/g). The extract demonstrates antioxidant properties, promotes hyaluronan synthesis in skin fibroblasts, reduces intraocular pressure, and shows potential benefits for eye conditions including glaucoma, cataracts, and dry eye disease.

Other names
CCEC. cicadae extractCCM-DWCCM-EtOH
02

Targets

HAS1 (Hyaluronan synthase 2)

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