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coriander essential oil

Development stage: Preclinical
Lead developer: Rīgas Stradiņš University
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Topical

Overview

Coriander essential oil is a botanical extract derived from *Coriandrum sativum* being investigated as a therapeutic mouthwash for the treatment of periodontitis. Developed by Riga Stradiņš University, the formulation leverages the antimicrobial and anti-inflammatory properties of its primary constituents, such as linalool and various terpenes. It is currently being evaluated in clinical trials to assess its impact on the salivary microbiome and markers of oral and systemic inflammation in patients with stage III periodontitis, serving as an adjunctive oral hygiene intervention compared to standard treatments like chlorhexidine.

Other names: Coriandrum sativum essential oilcoriander oil

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