coriandrum sativum extract

*Coriandrum sativum extract* refers to the extract of various parts (leaves, seeds, stems) of the Coriandrum sativum plant, commonly known as coriander or cilantro. It is traditionally used in several cultures for its medicinal and culinary properties. The extract contains multiple bioactive phytochemicals, such as linalool (the main constituent of the essential oil), flavonoids (e.g., quercetin, rutin, apigenin), phenolic acids, phytosterols, and vitamins[1][2]. **Mechanism of action:** - The extract exhibits cardioprotective properties through antioxidant, antihypertensive, hypolipidemic, anti-atherogenic, antiarrhythmic, and diuretic effects[2]. - Antihypertensive activity is partly due to inhibition of angiotensin-converting enzyme (ACE) by flavonoids, which also exert vasodilatory and nitric oxide–modulating effects[2]. - Neuroprotective and anxiolytic activities have been linked to linalool content and monoamine oxidase-B (MAO-B) inhibition[2][3]. - It may modulate memory and reduce anxiety, based on animal and emerging clinical data[3]. - Coriandrum sativum extract also exhibits anti-inflammatory, hypoglycemic, and analgesic properties, likely through interactions with pain receptors, inflammatory mediators, and glucose metabolism[1][2]. **Primary indications:** Traditionally used for hypertension, hyperlipidemia, diabetes, migraine, anxiety, and gastrointestinal complaints; recently explored for memory disorders and neuroprotection[1][2][3]. **Regulatory status:** Considered a functional food/nutraceutical; not an approved pharmaceutical for a specific indication.

Other names

coriander extractcilantro extractextract of Coriandrum sativumcoriander seed extractcoriander leaf extract