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corticosterone
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
Corticosterone is an adrenocortical steroid hormone with modest but significant activities as both a mineralocorticoid and a glucocorticoid. It is naturally produced in the adrenal cortex of vertebrates and plays roles in metabolic regulation and anti-inflammatory responses. Corticosterone participates in corticosteroid receptor-mediated anti-inflammatory responses and contributes to metabolic and homeostatic processes. It also plays a role in maintaining intraocular pressure by regulating aqueous humor secretion[2][7].
- Other names
- Kendall's compound BReichstein's substance H11beta,21-Dihydroxy-4-pregnene-3,20-dione(11β)-11,21-dihydroxypregn-4-ene-3,20-dione
02
Targets
GR (Glucocorticoid receptor)MR (Mineralocorticoid receptor)
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