Drug intelligence / Profile preview

Cosolv-DX

Development stage
Unknown
Lead developer
Emblazon Life Sciences
Modality
Small Molecules
Administration
Oral
01

Overview

Cosolv-DX is a combination pharmaceutical formulation marketed by the Indian company Emblazon Life Sciences for the symptomatic relief of dry cough and upper respiratory symptoms associated with the common cold or allergic rhinitis. It contains three active ingredients: dextromethorphan hydrobromide, chlorpheniramine maleate, and phenylephrine hydrochloride. Dextromethorphan is a centrally acting antitussive that suppresses the cough reflex by elevating the cough threshold in the brain. Chlorpheniramine is a first-generation antihistamine that blocks H1 receptors to alleviate allergic symptoms such as sneezing, runny nose, and watery eyes. Phenylephrine is a sympathomimetic decongestant that acts as an alpha-1 adrenergic agonist, causing vasoconstriction in the nasal mucosa to reduce congestion and swelling. The product is typically administered as an oral syrup.

Brand names
Cosolv-DX
Other names
Cosolv-DX-Emblaze
02

Targets

HRH1 (Histamine H1 Receptor)ADRA1A (α1A)SIGMAR1 (Sigma non-opioid intracellular receptor 1)NMDAR (Glutamate receptor ionotropic, NMDA)

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