counseling + OTP-Friends Research Institute, Inc.-heroin addiction

counseling + OTP-Friends Research Institute, Inc.-heroin addiction refers to a specific treatment arm within a Phase 3 clinical trial (NCT00574067) conducted by the Friends Research Institute. This protocol evaluates a sequential approach to treating heroin addiction in incarcerated individuals, where behavioral counseling is provided during the final months of prison, followed by a referral to a community-based Opioid Treatment Program (OTP) for the initiation of buprenorphine-naloxone therapy upon release. The pharmacological component, buprenorphine, is a partial mu-opioid receptor agonist and kappa-opioid receptor antagonist that mitigates withdrawal symptoms and cravings, while naloxone is included as a mu-opioid antagonist to deter intravenous misuse. This study specifically compared the effectiveness of this post-release initiation strategy against starting buprenorphine treatment while still in prison.

Brand names

Suboxone

Other names

Counseling + OTPBuprenorphine for Prisoners