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COVAXIN

Development stage
Phase 4
Lead developer
Bharat Biotech
Modality
Whole Inactivated Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

COVAXIN is a whole-virion inactivated SARS-CoV-2 vaccine developed for the prevention of COVID-19. It uses a traditional platform where the entire virus is grown in Vero cells and then inactivated with beta-propiolactone, rendering it non-infectious while preserving its ability to stimulate an immune response. The vaccine includes an aluminium-based adjuvant (Alhydroxiquim-II) to enhance immunogenicity. Developed by Bharat Biotech in collaboration with the Indian Council of Medical Research (ICMR) and National Institute of Virology (NIV), COVAXIN was India's first indigenous COVID-19 vaccine and has been widely used within India and approved for emergency use in several other countries. Its primary mechanism is to induce protective immunity against SARS-CoV-2 by presenting the immune system with all viral proteins, not just spike protein[1][2][3][4][6].

Brand names
COVAXIN
Other names
BBV152BBV-152BBV 152Bharat Biotech COVID-19 vaccineCovaxin (BBV152)
02

Targets

SARS-CoV-2 spikeM protein (SARS-CoV-2 membrane protein)N (Nucleocapsid protein)

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