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Coviccine Trivalent XBB
- Development stage
- Phase 3
- Lead developer
- WestVac Biopharma
- Modality
- Recombinant Protein Vaccines → Recombinant Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
- Administration
- Intramuscular
01
Overview
**Coviccine Trivalent XBB (WSK-V102C)** is a recombinant protein vaccine developed by WestVac BioPharma using an Sf9 insect cell platform. It targets SARS-CoV-2 by incorporating receptor-binding domains (RBDs) from XBB.1.5, BA.5, and Delta variants fused to the spike protein's heptad repeat (HR) domain, forming stable trimeric particles adjuvanted with a squalene-based oil-in-water emulsion. Primarily indicated as a booster for COVID-19 prevention in adults aged 18+, it elicits broad neutralizing antibodies against diverse Omicron sublineages including XBB descendants, JN.1, and BA.2.87.1, with demonstrated 93.28% protective efficacy against XBB.1, XBB.1.5, and XBB.1.9, and an excellent safety profile.[2][3][4]
- Brand names
- Coviccine Trivalent XBB
- Other names
- Recombinant COVID-19 Trivalent (XBB+BA.5+Delta) Protein Vaccine (Sf9 Cell)Trivalent recombinant protein COVID-19 vaccine - WestVac BiopharmaCoviccine® Trivalent XBB Vaccine (WSK-V102C)
02
Targets
RBD (SARS-CoV-2 spike receptor-binding domain)
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