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Drug intelligence / Profile preview
COVID-19 DNA vaccine candidate
- Development stage
- Unknown
- Lead developer
- Inovio Pharmaceuticals
- Modality
- Prophylactic Vaccines → Vaccines & Immunotherapeutics, DNA Vaccines → Plasmid DNA → DNA Therapeutics → Nucleic Acid Therapeutics
- Administration
- Intramuscular, Intradermal, Intranasal, Oral, Mucosal, Transdermal, Subcutaneous
01
Overview
This term is **non-specific** and does not identify a single unique product. It generally refers to an investigational **DNA plasmid vaccine** designed to prevent COVID-19 by delivering DNA encoding one or more SARS-CoV-2 antigens, most commonly the spike protein, so host cells transiently express the antigen and induce neutralizing antibody and T-cell responses. Multiple distinct COVID-19 DNA vaccine candidates were developed by different organizations during the pandemic, with varying constructs, delivery methods such as intradermal injection with electroporation, and development outcomes; therefore the term cannot be reliably mapped to one exact drug without an explicit product name or sponsor.
- Other names
- COVID-19 DNA vaccine candidateCOVID19 DNA vaccine candidateCOVID 19 DNA vaccine candidate
02
Targets
SARS-CoV-2 spike
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