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Drug intelligence / Profile preview
COVID-19-Influenza Combination vaccine
- Development stage
- Phase 4
- Lead developer
- Novavax
- Modality
- Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes, Nanoparticles → Drug Delivery Systems
- Administration
- Intramuscular
01
Overview
The COVID-19-Influenza Combination (CIC) vaccine is an investigational protein-based combination vaccine developed by Novavax. It combines the company's recombinant protein-based COVID-19 vaccine (NVX-CoV2373) with its quadrivalent nanoparticle influenza vaccine candidate into a single formulation. The vaccine utilizes Novavax's proprietary recombinant nanoparticle technology to produce hemagglutinin (HA) antigens for four influenza strains and the spike (S) protein antigen for SARS-CoV-2. It is formulated with the patented saponin-based Matrix-M adjuvant to enhance the immune response. Designed for intramuscular administration and stored at standard refrigeration temperatures (2-8°C), the vaccine aims to provide simultaneous protection against both seasonal influenza and COVID-19.
- Other names
- Novavax COVID-19-Influenza Combination vaccine
02
Targets
HA (Hemagglutinin)SARS-CoV-2 spike
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