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Drug intelligence / Profile preview
COVID-19 recombinant protein vaccine
- Development stage
- Approved
- Lead developer
- Novavax
- Modality
- Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
- Administration
- Intramuscular
01
Overview
COVID-19 recombinant protein vaccines are a class of protein subunit vaccines designed to prevent COVID-19 by presenting a laboratory-engineered version of the SARS-CoV-2 spike protein to the immune system. Unlike mRNA or viral vector vaccines, these products deliver the antigen directly, typically in combination with an adjuvant (such as Novavax's Matrix-M or Sanofi's AS03) to enhance immunogenicity. This technology is used in authorized vaccines like Nuvaxovid (Novavax) and VidPrevtyn Beta (Sanofi/GSK). In clinical research, such as studies conducted by the Finnish Institute for Health and Welfare (THL), the term is used to categorize these authorized biologics when evaluating real-world immune responses and vaccine effectiveness against SARS-CoV-2 variants.
- Brand names
- NuvaxovidCovovaxVidPrevtyn BetaSKYCovione
- Other names
- SARS-CoV-2 recombinant protein vaccineSARS-CoV2 recombinant protein vaccineSARS-CoV 2 recombinant protein vaccineCOVID-19 protein subunit vaccineCOVID19 protein subunit vaccineCOVID 19 protein subunit vaccine
02
Targets
BVDV E2 (Bovine viral diarrhea virus glycoprotein E2)SARS-CoV-2 spike
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