Drug intelligence / Profile preview

COVIGEN

Development stage
Phase 1
Lead developer
Technovalia
Modality
DNA Vaccines → Plasmid DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Prophylactic Vaccines → Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

COVIGEN is a plasmid DNA-based vaccine candidate against SARS-CoV-2, developed by BioNet-Asia in collaboration with Technovalia as part of an Australian COVID-19 vaccine program. It encodes viral antigen sequences intended to induce protective humoral and cellular immune responses against COVID-19 and is delivered intramuscularly using PharmaJet’s Stratis needle-free jet injection system in early clinical studies.[4][10] Preclinical data showed acceptable safety and immunogenicity, leading to a Phase 1/1b trial in healthy adults to assess safety, tolerability, and immune responses as a potential prophylactic vaccine for COVID-19.[4][10]

Brand names
COVIGEN
Other names
BioNet SARS-CoV-2 DNA vaccineTechnovalia COVID-19 DNA vaccineSARS-CoV-2 DNA vaccineSARS-CoV2 DNA vaccineSARS-CoV 2 DNA vaccine
02

Targets

SARS-CoV-2 spike

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