Drug intelligence / Profile preview

CoVLP (trivalent)

Development stage
Unknown
Lead developer
Medicago
Modality
Nanoparticles → Drug Delivery Systems, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

CoVLP (trivalent) is an enveloped virus-like particle (eVLP) vaccine candidate developed by Sferogen for the prevention of COVID-19. The vaccine is produced using Sferogen's eVLP platform, which generates non-infectious particles that mimic the structural characteristics of the SARS-CoV-2 virus. By presenting viral antigens in this native-like conformation, the vaccine is designed to elicit robust neutralizing antibody and T-cell immune responses. As a trivalent formulation, it is intended to provide broad protection against multiple variants of the SARS-CoV-2 virus. The candidate is currently in Phase 1 clinical development.

Other names
CoVLP-Sferogen-SARS-CoV-2-enveloped virus-like particle (eVLP) vaccine-COVID-19eVLP/SARS-CoV-2 vaccine
02

Targets

SARS-CoV-2 spike

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