Drug intelligence / Profile preview

CP-001

Development stage
Preclinical
Lead developer
Hanpoong Pharm
Administration
Oral
01

Overview

**CP-001** is an orally administered standardized four-herb mixture developed for atopic dermatitis. It contains extracts of *Houttuynia cordata*, *Rehmannia glutinosa*, *Betula platyphylla*, and *Rubus coreanus* and was standardized in a published preclinical study to catalpol, quercitrin, and ellagic acid marker contents. The product has shown preclinical anti-inflammatory and antiallergic activity in atopic-dermatitis models, but it has no established single molecular target or defined clinical mechanism. CP-001 was evaluated clinically as the related functional-food product KM110329 in a randomized, double-blind, placebo-controlled study in adults with mild-to-moderate atopic dermatitis. ([ncbi.nlm.nih.gov](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723148/))

Other names
KM110329KM-110329KM 110329
02

Targets

Cyp (Cyclophilin family)

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