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CP-870,893 + cisplatin + pemetrexed is a combination therapy consisting of a CD40 agonist monoclonal antibody (CP-870,893) and two chemotherapy agents (cisplatin and pemetrexed). CP-870,893 activates antigen-presenting cells, triggers inflammatory cytokine release, and enhances antitumor cellular immunity. When combined with chemotherapy, it may facilitate tumor antigen release, potentially enhancing the overall antitumor effect.
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