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CP205 is a long-acting injectable (LAI) biologic formulation of butyrylcholinesterase (BChE) being developed by Consegna Pharma as a medical countermeasure for nerve agent exposure. The drug is designed to provide sustained protection, potentially up to 21 days, against organophosphate poisoning. It functions as a bioscavenger, utilizing the BChE enzyme to sequester and neutralize nerve agents in the systemic circulation before they can reach and irreversibly inhibit acetylcholinesterase at the neuromuscular junction and in the central nervous system. The program leverages Consegna's proprietary computational technology to optimize the delivery and pharmacokinetics of the recombinant enzyme.
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