Drug intelligence / Profile preview

CQ31

Development stage
Unknown
Lead developer
Memorial Sloan Kettering Cancer Center
01

Overview

CQ31: sourced facts only. name: "We recently reported that a dual inhibitor of the Xaa-Pro-cleaving M24B aminopeptidases PEPD and XPNPEP1 called CQ31 selectively activates the CARD8 inflammasome by inducing the build-up of Xaa-Pro peptides." [PMID:36724486]; target: "We recently reported that a dual inhibitor of the Xaa-Pro-cleaving M24B aminopeptidases PEPD and XPNPEP1 called CQ31 selectively activates the CARD8 inflammasome by inducing the build-up of Xaa-Pro peptides." [PMID:36724486]; target: "We recently reported that a dual inhibitor of the Xaa-Pro-cleaving M24B aminopeptidases PEPD and XPNPEP1 called CQ31 selectively activates the CARD8 inflammasome by inducing the build-up of Xaa-Pro peptides." [PMID:36724486]; developer: "Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States." [PMID:36724486]

02

Targets

PEPD (Peptidase D (prolidase))XPNPEP1 (X-prolyl aminopeptidase 1)

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