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Drug intelligence / Profile preview
crack cocaine
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Inhalation
01
Overview
Crack cocaine is a free base form of the stimulant cocaine, derived from the leaves of the coca plant. It is produced by processing powdered cocaine (cocaine hydrochloride) with a base like sodium bicarbonate (baking soda) and water, then heating the mixture to form solid, rock-like crystals. When smoked, it produces a rapid, intense, but short-lived euphoric high due to quick absorption into the bloodstream. It is a powerfully addictive central nervous system stimulant.
- Other names
- crackrock
02
Targets
SERT (Sodium-dependent serotonin transporter)DAT (Dopamine plasma membrane transport protein)NET (Norepinephrine Transporter)NaV (Voltage-gated sodium channels)
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